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Adding cetuximab to chemotherapy enables patients with advanced colorectal...

New results from a clinical trial conducted in Shanghai, China, indicate that adding cetuximab (Erbitux) to standard chemotherapy enables some patients with otherwise inoperable liver metastases due to...

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Liver cancers armed with many strategies for evading immune response

(Medical Xpress)—Researchers at Roswell Park Cancer Institute (RPCI) have published findings that help explain how a common and particularly resilient form of liver cancer evades the body's natural...

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Metastasis stem cells in the blood of breast cancer patients discovered

Individual cancer cells that break away from the original tumor and circulate through the blood stream are considered responsible for the development of metastases. These dreaded secondary tumors are...

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Frequently used biologic agents might cause acute liver injury

A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official...

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Upper GI bleed linked to death from other causes

Individuals who have experienced a major bleed from their stomach or oesophagus (known as an upper gastrointestinal bleed) may be more likely to die from other causes, particularly malignant tumours...

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Targeted therapy sorafenib shows success in advanced differentiated thyroid...

The kidney and liver cancer drug sorafenib holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which will be presented...

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Targeted stimulation of immune pathway may help body fight back against liver...

Though it originates from the body's own cells, a tumor is as much of a hostile invader as any virus or bacterium. If the immune system is sufficiently sensitized, it can mount a counterattack just as...

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New evidence for genetic bases of liver cancer reported

The Asian Cancer Research Group (ACRG), an independent, not-for-profit company in collaboration with BGI, the world's largest genomics organization, and The University of Hong Kong (HKU), jointly...

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Pharmaceutical sciences research paper says vitamin D inhibits cancer...

Doctoral research student Shuang Zhou, and Erxi Wu, assistant professor of pharmaceutical sciences, have co-written a paper, "1, 25(OH)2D3 Inhibits Hepatocellular Carcinoma Development Through Reducing...

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Researchers unveil findings on two new weapons against thyroid cancer

For many years, patients with advanced thyroid cancer faced bleak prospects and no viable treatment options. But now, building on recent discoveries about the genetics and cell signaling pathways of...

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Liver cancer vaccine effective in mice

Tweaking a protein expressed by most liver cancer cells has enabled scientists to make a vaccine that is exceedingly effective at preventing the disease in mice.

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How metastases develop in the liver

In order to invade healthy tissue, tumor cells must leave the actual tumor and enter the bloodstream or lymphatic system. For this purpose, they use certain enzymes, proteases that break down the...

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Tumor microenvironment of hepatitis B virus-associated hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over recent years. Globally, there are approximately 750,000 new cases of liver...

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Erectile dysfunction drugs could protect liver from sepsis-induced damage

Drugs that are on the market to treat erectile dysfunction (ED) could have another use—they might be able to protect the liver from damage caused by sepsis, a systemic inflammatory response to...

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Plant extract fights brain tumour

Silibinin has an outstanding safety profile in humans and is currently used for the treatment of liver disease and poisoning. Scientists at the Max Planck Institute of Psychiatry in Munich discovered...

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Study paves way for early detection of liver cancer

Led by Georgia State University, researchers have developed the first robust and noninvasive detection of early stage liver cancer and liver metastases, in addition to other liver diseases, such as...

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Diagnosing cancer with help from bacteria

Engineers at MIT and the University of California at San Diego (UCSD) have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics—beneficial bacteria similar...

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Researchers find new method to halt the advance of liver cancer

A new study by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP), the National Cancer Institute, and the Chulabhorn Research Institute has found that blocking the activity of a...

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Team examines risk factors/patient outcomes associated with colorectal cancer

About 20 percent of colorectal cancer patients have cancers that have spread (metastasized) beyond the colon at the time of their diagnosis. The liver is the most common site for these metastases. The...

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New DNA testing for liver cancer could improve survival

Detection of small fragments of tumor DNA, known as circulating tumor DNA, in a patient's pre-surgery serum samples predicts early recurrence of hepatocellular carcinoma and may guide treatment,...

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