Metabolic shift may offer early cancer clue
Cancer cells are well known for their altered metabolisms, which may help them generate the energy they need for rapid growth. Using an emerging imaging technology, researchers reporting in the July...
View ArticleMetabolic profiles essential for personalizing cancer therapy
One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism shows that one metabolism-targeted cancer therapy will not fit...
View ArticleNew research sheds light on the molecular mechanisms by which a virus...
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk...
View ArticleA novel oncogenic network specific to liver cancer initiation
Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible...
View ArticleMouse model could help identify viral vectors that may cause tumors
Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect....
View ArticleIdentification of mutations common to half of all liver cancers provides...
Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-associated deaths. Yet even for such a frequent and deadly disease, the pathogenesis of this cancer remains...
View ArticlePaired CT scans catch chemo-killing of liver tumors in real time
Using two successive pairs of specialized CT scans, a team of Johns Hopkins and Dutch radiologists has produced real-time images of liver tumors dying from direct injection of anticancer drugs into the...
View Article'Microbeads' may boost survival in advanced colon cancer patients
(HealthDay News) —For advanced colon cancer patients who have developed liver tumors, so-called "radioactive beads" implanted near these tumors may extend survival nearly a year longer than among...
View ArticleNew ablation technique holds promise for liver cancer patients
A new minimally invasive tumor ablation technique is providing hope for liver cancer patients who can't undergo surgery or thermal ablation, a study shows.
View ArticleClinical trials helped one woman's fight against cancer
(HealthDay)—Monica Barlow, a 35-year-old from Maryland, was training for a half-marathon when she noticed she couldn't shake a bad cough and ongoing fatigue. After a couple of rounds of antibiotics...
View ArticleNew discoveries pave the way for early screening of liver cancer patients for...
Latest research findings by scientists at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) could enable early screening of patients with...
View Article'Undruggable' may be druggable: A new target for cancer drug development
Harvard Stem Cell Institute (HSCI) researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug...
View ArticleWhen injected as a hydrogel rather than in solution, an anticancer protein...
Proteins and other therapeutic compounds injected directly into the blood stream tend to be broken down rapidly by the immune system. Now, researchers in Singapore have demonstrated in mice that the...
View ArticleLiver tumors found in mice exposed to BPA
In one of the first studies to show a significant association between BPA and cancer development, University of Michigan School of Public Health researchers have found liver tumors in mice exposed to...
View ArticleY-90 provides new, safe treatment for metastatic breast cancer
A minimally invasive treatment that delivers cancer-killing radiation directly to tumors shows promise in treating breast cancer that has spread to the liver when no other treatment options remain,...
View Article3-D MRI scans may offer better way to predict survival after chemo for liver...
In a series of studies involving 140 American men and women with liver tumors, researchers at Johns Hopkins have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to...
View ArticleFaster, safer method zaps tumors with great success
(Medical Xpress)—When Kevin McSweeney was referred to UW Health last year for a tumor in his liver, he had already gone through six rounds of chemotherapy and 13 surgeries over 10 years to treat his...
View ArticleA new way to model cancer
Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic...
View ArticleEffect of chemotherapy on surgical resection of liver tumors
A study of pediatric patients with hepatoblastoma led by researchers at Children's Hospital Los Angeles (CHLA) suggests an opportunity to reduce chemotherapy in up to 65 percent of patients, which...
View ArticleFDA expands approval of Bayer cancer drug (Update)
The U.S. Food and Drug Administration on Monday expanded approval of a Bayer cancer pill to treat tumors of the intestinal tract that do not respond to other treatments.
View Article