Researchers find new method to halt the advance of liver cancer
A new study by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP), the National Cancer Institute, and the Chulabhorn Research Institute has found that blocking the activity of a...
View ArticleTeam examines risk factors/patient outcomes associated with colorectal cancer
About 20 percent of colorectal cancer patients have cancers that have spread (metastasized) beyond the colon at the time of their diagnosis. The liver is the most common site for these metastases. The...
View ArticleNew DNA testing for liver cancer could improve survival
Detection of small fragments of tumor DNA, known as circulating tumor DNA, in a patient's pre-surgery serum samples predicts early recurrence of hepatocellular carcinoma and may guide treatment,...
View ArticleRetroviral RNA may play a part in liver cancer
An international group led by RIKEN in Japan and INSERM in France have found that retroviral long-terminal-repeat (LTR) promoters—a type of repetitive element that are widely distributed in the human...
View ArticlePredicting cancer's growth from few clues
Mathematicians at Duke University are developing ways to help doctors predict how different cancers are likely to progress when actual measurements of tumor growth are hard to come by.
View ArticleScientists root out the 'bad seeds' of liver cancer
Researchers have found the 'bad seeds' of liver cancer and believe they could one day reprogram them to remain responsive to cancer treatment, a new study has found.
View ArticleWhen the immune system promotes tumor growth
The immune system protects the body against cancer cells. The Elimination of cancer cells is an important task of NK cells. For NK cells to function properly, they require the activator STAT5.
View ArticleAdding immunotherapy to RFA may benefit colorectal cancer patients with liver...
Radiofrequency ablation (RFA), a procedure to treat liver metastases in patients with colorectal cancer, was found to induce antitumor immune responses in human samples of primary colon tumor, and mice...
View ArticleResearchers discover liver metastases have different radiation sensitivities...
Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to...
View ArticleMonitoring sugar metabolism in liver may be a key to cancer diagnosis
Scientists may have discovered a significant new diagnostic marker for liver cancer, according to a paper published in the April 18 online issue of Nature Cell Biology.
View ArticleLung tumors hijack metabolic processes in the liver, study finds
University of California, Irvine scientists who study how circadian rhythms—our own body clocks—control liver function have discovered that cancerous lung tumors can hijack this process and profoundly...
View ArticlePancreatic cancer paves the path for metastases in the liver at an...
Pancreatic cancer is an exceptionally aggressive type of cancer. Frequently, metastases already start to grow in other organs, particularly often in the liver, before the original tumor was even...
View ArticleResearch uncovers defender against cancer-promoting liver damage
Most cases of liver cancer develop after long-term viral infection, chronic exposure to alcohol, or excessive accumulation of fat in the liver due to obesity. The liver reacts to those insults by...
View ArticleStudy identifies possible mechanism for resistance to antiangiogenesis therapy
Massachusetts General Hospital (MGH) investigators have identified a potential mechanism behind the resistance that inevitably develops to cancer treatment with a combination of chemotherapy and...
View ArticleJet lag and obesity share similar pathways to liver cancer
Since 1980, the incidence of hepatocellular carcinoma, the most common type of liver cancer, has nearly tripled, and obesity related liver disease is one of the driving forces behind the increasing...
View ArticleUnexpected activity of two enzymes helps explain why liver cancer drugs fail
Some cancers are caused by loss of enzymes that should keep cell growth in check. On the flip side, some are caused by over-activation of enzymes that enhance cell growth. Yet drugs that inhibit the...
View ArticleOne more piece in the puzzle of liver cancer identified
Manuela Baccarini and her team at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and Medical University of Vienna are one step closer to unraveling the mechanisms behind liver...
View ArticleLiver tumor growth in mice slowed with new chemo-immunotherapy treatment
Hepatocellular carcinoma is the most common form of liver cancer, but treatment options are limited and many patients are diagnosed in late stages when the disease can't be treated. Now, University of...
View ArticleScientists stimulate immune system, stop cancer growth
A chemical found in tumors may help stop tumor growth, according to a new study.
View ArticleStudy identifies a role for the metabolism regulator PPAR-gamma in liver cancer
Liver cancers are a major cause of cancer-related deaths. Large-scale genetic analyses have associated liver cancer with dysregulation of numerous molecular pathways, but disruptions in insulin...
View ArticleScrib protein identified as a natural suppressor of liver cancer
A protein that typically helps keep cells organized and on task becomes a tumor suppressor in the face of liver cancer, scientists say.
View ArticleColorectal tumors initiate VEGF-A/CXCL1 cascade, creating distant niches for...
Primary colorectal tumors secrete VEGF-A, inducing CXCL1 and CXCR2-positive myeloid-derived suppressor cell (MDSC) recruitment at distant sites and establishing niches for future metastases, report...
View ArticleLiquid biopsy may be new way to detect liver cancer earlier, easier
An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating...
View ArticleTeam finds a potentially better way to treat liver cancer
A Keck School of Medicine of USC research team has identified how cancer stem cells survive. This finding may one day lead to new therapies for liver cancer, one of the few cancers in the United States...
View ArticleUltra-personal therapy: Gene tumor boards guide cancer care
Doctors were just guessing a decade ago when they gave Alison Cairnes' husband a new drug they hoped would shrink his lung tumors. Now she takes it, but the choice was no guesswork. Sophisticated gene...
View ArticleAcross Asia, liver cancer is linked to herbal remedies: study
Researchers have uncovered widespread evidence of a link between traditional Chinese herbal remedies and liver cancer across Asia, a study said Wednesday.
View ArticleHow chronic inflammation tips the balance of immune cells to promote liver...
Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and...
View ArticleA new strategy for prevention of liver cancer development
Primary liver cancer is now the second leading cause of cancer-related death worldwide, and its incidences and mortality are increasing rapidly in the United Stated. In late stages of the malignancy,...
View ArticleStudy suggests colon cancer cells carry bacteria with them when they metastasize
(Medical Xpress)—A team of researchers working at Harvard University has found evidence that suggests a certain type of bacteria found in colon cancer tumors makes its way to tumors in other body parts...
View ArticleLiver cancer: Lipid synthesis promotes tumor formation
Lipids comprise an optimal energy source and an important cell component. Researchers from the Biozentrum of the University of Basel and from the University of Geneva have now discovered that the...
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